Scientist Profile
















Details of Research Publications (National + International)

Author Names Topic Journal Name Volume Number Issue Number Page Number Year Published Impact Factor
Trivedi, V., Gupta, A., Rao, J.V.K., Saravanan, P., Rao, G.S.J., Rao, A.N., Savithri, H.S. and Subramanya, H.S. Crystal Structure of Binary and Ternary Complexes of Serine Hydroxymethyl-transferase from B.Stearothermophilus: Insights into the Catalytic Mechanism. J. Biol. Chem. 277 17161-17169 2002
Sarkhel, S., Sharon, A., Trivedi, V., Maulik, P. R., Singh, M. M., Venugopalan, P., Ray, S. Structure-Based Drug Design : Synthesis, Crystal Structure, Biological Evalution and Docking Studies of Mono- and Bis-Benzo[b] Oxepines as Non-steroidal estrogens. Bioorg.Med.Chem. 11 5025-5033 2003
Bhavani S., Trivedi V., Ambili M., Jala V.R., Subramanya H.S., Purnima K., Appaj R.N., Savithri, H.S. Role of Lys-226 in the Catalytic Mechanism of Bacillus Stearothermophilus Serine Hydroxymethyl-transferase – Crystal Structure  and Kinetic Studies. Biochemistry 44 18 6929 -6937 2005
Trivedi, V ., Srivastava, K., Puri, S.K., Maulik, P.R ., Bandyopadhyay, U Purification and Biochemical Characterization of a Heme Containing Peroxidase from the Human Parasite P. falciparum. Protein  Expr Purif. 37 2 154-161 2005
Trivedi, V., Chand, P., Maulik, P. R., Bandyopadhyay, U. Mechanism of Horseradish Peroxidase - Catalyzed Heme Oxidation and Polymerization (β--Hematin formation). Biochem. Biophys. Acta. 1723 221-228 2005
Trivedi, V., Chand, P., Srivastava, K., Puri, S. K., Maulik, P. R., Bandyopadhyay, U. Clotrimazole Inhibits Hemo- Peroxidase of P. falciparum and Induces Oxidative Stress : Proposed Antimalarial Mechanism of Clotrimazole. J. Biol. Chem. 280 41129-41136 2005
Stockinger W, Zhang, S.C., Trivedi, V, Jarzylo, L. A., Shieh, E. C., Lane, W.S., Castoreno, A. B. and Nohturfft,A Differential Requirements for Actin Polymerization, Calmodulin and  Ca2+ Define Distinct Stages of Lysosome/Phagosome Targeting. Mol. Biol. Cell 17 1697-1710 2006
Trivedi, V.,Zhang, S.C., Castoreno, A.B.,  Stockinger W, Shieh, E.C., Vyas, J.M., Frickel, E and Nohturfft, A. Immunoglobin G Signaling Activates Phagosome/Lysosome Targeting. Proc Natl Acad Sci U S A. 103 48 18226-18231 2006
Trivedi, V, Zhang, SC,  Stockinger, W  and Nohturfft, A A Cell-Free Scintillation Proximity Assay for Studies on Lysosome-to-Phagosome Targeting. Science STKE, 2007 392 13 2007
Ahmad, R., Raina, D., Trivedi, V., Ren, J., Rajabi, H., Kharbanda, S., Kufe, D. MUC1 Oncoprotein activates the IkB kinase β Complex and Constitute NF-κB Signaling. Nature Cell Biology 9 1419-1427 2007
Trivedi, V, Adrienne Boire, Boris Tchernychev, Nicole Kaneider, Andrew J Ledger, Katie O’ Callaghan, Lidija Covic & Athan Kuliopulos Platelet Matrix Metalloprotease-1 Mediates Thrombogenesis By Activating PAR1 At A Novel Cryptic Ligand Site. Cell 137 2 332-343 2009
Balaji, SN and Trivedi, V* Extracellular Methemoglobin mediated early ROS spike triggers osmotic fragility and RBC destruction: An Insight into the enhanced hemolysis during malaria. Ind J Clin Biochem 27 2 178-185 2012
Trivedi, V* and Nag, S In Silico Characterization of Atypical Kinase, PFD0975w from plasmodium kinome: A suitable target for drug discovery. Chem Biol Drug Des. 79 4 600-609 2012
Prasad, KMN and Trivedi, V* Engineering High Resolution Horizontal Native PAGE for Proteins. International Research Journal of Biotechnology 3 4 40-46 2012
Nag, S., Prasad, KMN and Trivedi, V Identification and screening of antimalarial Phytochemical reservoir from northeastern Indian plants to develop PfRIO-2 Kinase Inhibitor. Eur Food Res Technol, 234 905-911 2012
Nag, S., Prasad, KMN., Bhowmick, A., Deshmukh, R., Trivedi, V PfRIO-2 Kinase is a potential therapeutic target of antimalarial protein kinase inhibitors. Curr Drug Discov Technol 10 85-91 2013
Deshmukh, R., Trivedi, V Methemoglobin exposure produces toxicological effects in macrophages due to multiple ROS spike induced apoptosis. Toxicology in Vitro 27 16-23 2013
Dwivedi, A., Prasad, KMN., Trivedi, V., Iyer, P Interaction of Heme Proteins with Anionic Polyfluorene: In-sights into Physiological Effects, Folding Events and Inhibition Activity. Appl. Mater. Interfaces 4 11 6371–6377 2012
Balaji, SN and Trivedi, V Extracellular Methemoglobin Primes Red Blood Cell Aggregation in Malaria: An In-Vitro Mechanistic Study. FEBS Letters 587 350-357 2013
Balaji, SN and Trivedi, V Methemoglobin incites the primaquine toxicity through single electron oxidation and modification. J Basic Clin Physiol Pharmacol 24 2 105–114 2013
Balaji, SN and Trivedi, V Mechanism based suicidal inactivation of methemoglobin protects oxidative stress induced RBC lysis: Role of thiyl radicals of NAC in antioxidant potentials. Current Molecular Medicine 13 6 1000-1009 2013
Deshmukh, R and Trivedi, V* Pro-stimulatory role of methemoglobin in inflammation through Hemin Oxidation and Polymerization. Inflamm Allergy Drug Targets 12 1 68-78 2013
Nag, S., Chouhan, DK., Balaji, SN., Chakraborty, A., Lhouvum, K., Bal, C., Sharon, A and Trivedi, V Comprehensive screening of heterocyclic compound libraries to identify novel inhibitors for PfRIO-2 kinase through docking and substrate competition studies. Med Chem Res 22 4737-4744 2013
Lhouvum, K., Ramakrishnan, V and Trivedi, V Insight into structural and Biochemical determinants of substrate specificity of PFI1625c: Correlation analysis of protein-peptide molecular models. J of molecular graphics and modeling 43 21-30 2013
Manu S, Rohitas Deshmukh, KMN Prasad and Trivedi, V Screening and Characterization of Antimalarial Heme Polymerase Inhibitors From Dietary Garlic Cloves. European journal of medicinal plants 3 3 474-484 2013
Afsana Parween, Arnish Chakraborty, Ananda Kumar Konreddy, Harapriya Chakravarty, Ashoke Sharon, Vishal Trivedi*, Chandralata Bal Skeletal hybridization and PfRIO-2 kinase modeling for synthesis of α-pyrone analogs as anti-malarial agent. European Journal of Medicinal Chemistry 70 607-612 2013
Deshmukh, R and Trivedi, V Methemoglobin Mediated Immuno-Toxicity Modulation Of Pro-Oxidant Molecules Towards Macrophage During Malaria. Mol Microbiol. 9 7 2013

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